Multisystem Inflammatory Syndrome in Children

Multisystem inflammatory syndrome in children (MIS-C) is an uncommon but emerging syndrome related to SARS-CoV-2 infection. While the presentation of MIS-C is generally delayed after exposure to the virus that causes coronavirus 2019, both MIS-C and Kawasaki disease (KD) share similar clinical features. Multisystem inflammatory syndrome in children poses a diagnostic and therapeutic challenge given the lack of definitive diagnostic tests and a paucity of evidence regarding treatment modalities. We review the clinical presentation, diagnostic evaluations, and management of MIS-C and compare its clinical features to those of KD.

Efficient Centroid Based Distance Monitoring System Using Deep Learning

COVID-19 virus spread very rapidly if we come in contact to the other person who is infected, this was treated as acute pandemic. As per the data available at WHO more than 663 million infected cases reported and 6.7 million deaths are confirmed worldwide till Dec, 2022. On the basis of this big reported number, we can say that ignorance can cause harm to the people worldwide. Most of the people are vaccinated now but as per standard guideline of WHO social distancing is best practiced to avoid spreading of COVID-19 variants. This is difficult to monitor manually by analyzing the persons live cameras feed. Therefore, there is a need to develop an automated Artificial Intelligence based System that detects and track humans for monitoring. To accomplish this task, many deep learning models have been proposed to calculate distance among each pair of human objects detected in each frame. This paper presents an efficient deep learning monitoring system by considering distance as well as velocity of the object detected to avoid each frame processing to improve the computation complexity in term of frames/second. The detected human object closer to some allowed limit (1m) marked by red color and all other object marked with green color. The comparison of with and without direction consideration is presented and average efficiency found 20.08 FPS (frame/Second) and 22.98 FPS respectively, which is 14.44% faster as well as preserve the accuracy of detection. © 2023 IEEE.

Smart-thing design by children at a distance: How to engage them and make them learn

In recent years, research in Child-Computer Interaction has shifted the focus from design with children, giving them a voice in the design process, to design by children to bring child participants different benefits, such as engagement and learning. However, design workshops, encompassing different stages, are challenging in terms of engagement and learning, e.g., they require prolonged commitment and concentration. They are potentially more challenging when held at a distance, as in recent years due to the COVID-19 pandemic. This paper explores at-a-distance smart-thing design by children, how it can engage different children and support their learning in programming. The paper reports a series of design workshops with 20 children, aged from 8 to 16 years old, all held at a distance. They were all organised with the DigiSNaP design framework and toolkit. The first workshop enabled children to explore what smart things are, to start ideating their own smart things and to scaffold their programming. The other workshops enabled children to evolve their own smart-thing ideas and programs. Data were gathered in relation to children's engagement and learning from different sources. Results are promising for future editions of smart-thing design at a distance or in a hybrid modality. They are discussed along with guidelines for smart-thing design by children at a distance. (PsycInfo Database Record (c) 2023 APA, all rights reserved)

Comprehensive review about automatic classification of medicinal plants

The word Taxonomy is the way of Classification. It is the science of naming and classifying all the living organisms as well as extinct organisms of the world. Swedish Botanist Carlous Linnaeus was the father of taxonomy;Out of 17000 plant species present in India, more than 7600 plants are medicinal plants. Indigenous Indian medicines are formulations of traditional knowledge and medicinal plant extracts. The traditional knowledge is transferred from one generation to other generations which is used as drug for various diseases, instead of relying on what is the ingredients and proportions these drugs are based on traditional knowledge. These drugs involve the use of plant extract. The World Health Organization (WHO), leading agency in health care found that 80 % population in low economic output countries depend on traditional medicine for their essential health care[1]. In the current era of pandemic medicinal plant species like citrus spp, allium sativum, allium cepa found effective in management of COVID 19. As per WHO guidelines, In the field of medicinal research where clinical trials are used for new drug discovery, there is need of continuous supply of authenticated products which are correctly identified, classified, and verified [1]. Traditional identification and classification methods are not quick, efficient and reliable. Automated Classification of medicinal Plants help to conserve knowledge of medicinal plant species, share it from one generation to next generation and help the whole society to improve the knowledge about medicinal plants. The paper presents traditional and recent trends using Computer vision and machine learning for classifying medicinal plant species. The main focus is on Leaf image as input. It presents the challenges as well as opportunities in identifying and classifying medicinal plant species by performing comprehensive review of traditional methodologies. © 2023 Author(s).

Microbiological diagnosis of Clostridioides difficile infec- tion in times of COVID-19 in a high complexity pediatric hospital

Clostridioides difficile infection (CDI) can cause anything from diarrhea to toxic megacolon. The objectives of this study were: to show the varia-tion in the number of diagnosed cases of CDI in this center, comparing 2020, when the COVID-19 pandemic began, with 2019 and 2021 and to detail cases preceded by SARS-CoV-2 infection. This is an observational retrospective study in which the total number of samples processed with suspected CDI were recorded. The positive ones and the clinical history of patients with a diagnosis of CDI up to two months after their diagnosis of SARS-CoV-2 infection were recorded as well. During 2020 a smaller number of samples were processed. However, during this year the percentage of positivity was 13.1% vs. 7,2% and 7.8% during 2019 and 2021, respectively. It is believed that this may have been due to improvements in clinical suspicion and sample selection for CDI diagnosis.

The Dissemination and Implementation of Recess Guidelines, Policies, and Practices During the COVID-19 Pandemic

Purpose: There are limited school physical activity policy dissemination and implementation studies. This is a concern given the adverse mental, physical, and socio-emotional effects the COVID-19 pandemic has had on children and adolescents. This study explored New Jersey school administrators' experiences in disseminating recess guidelines, procedures, and policies as well as implementation strategies in their schools during the pandemic. Methods: A total of 29 elementary school administrators participated in semi-structured interviews. The data were analyzed inductively using a conventional approach to qualitative content analysis. Results: In analyzing the data, five themes were identified: (a) adjustments for recess, (b) communications about recess, (c) successes and challenges of recess, (d) health and well-being among children, and (e) recommendations for recess postpandemic. Discussion/Conclusion: When planning, organizing, and implementing a recess in a postpandemic era, school leaders may want to consider establishing cohorts, developing a handbook, creating a rotation schedule (i.e., blacktop, field, playground), developing a recess committee, utilizing the physical education teacher for staff development, assigning recess equipment and bags, offering a variety of activities, and teaching children how to play.

Implementation of the healthy school construction plan to promote students' health and well-being

With the development of society, the health and well-being of children and adolescents are receiving increasing attention from the government and scholars. The implementation of the health (promoting) school construction plan has a significant effect on promoting students' health and well-being, which is especially important in the normalized stage of COVID-19 epidemic prevention and control. The study summarizes the importance of health (promoting) schools for students' health and well-being, reviews the development of health (promoting) school construction in China, and proposes countermeasures and recommendations to further promote health (promoting) school construction in China in the light of the new era.

Surviving Sepsis Campaign COVID-19 Panel

In late 2019, a new coronavirus, called severe acute respiratory syndrome coronavirus 2, led to an epidemic of acute respiratory syndrome and subsequently to a pandemic. The Surviving Sepsis Campaign COVID-19 expert group developed 54 urgent statements on the management of COVID-19 in the intensive care unit, of which 4 are best practice statements, 9 are strong recommendations, and 35 are weak recommendations. The authors did not undertake a new systematic prioritization of results but used the current work of the Surviving Sepsis Campaign Guideline 2020 and expert opinion. The Surviving Sepsis Campaign COVID-19 Panel is divided into 4 groups: 1) infection control and testing: identification of aerosol-generating proce-dures, healthcare workers perform aerosol-generating procedures in a negative pressure room, using appropriate respiratory masks (N95 respirators, FFP2) and protective equipment (gloves, gown, eye protection, etc.);2) laboratory monitoring and specimens: each patient admitted to the intensive care unit with signs of respiratory infection should be considered as potentially infected with severe acute respiratory syndrome, and samples from the lower airways should be obtained after intubation and ventilation for diagnostic testing;3) hemodynamic support;4) respiratory support. The Grading of Recommendations, Assessment, Deve-lopment approach was used to assess the quality of evidence. The quality of evidence was assessed as high, moderate, low and very low. Online software was used — GDT (http://gdt.guidelinede-velopment.org) to generate the evidence profiles. © 2022, Zaslavsky Publishing House. All rights reserved.

Towards a classification of vulnerability of small-scale fisheries

Vulnerability of small-scale fisheries (SSF) results from complex interactions amongst various threats and stressors, including biophysical risks, environmental variability, unstable political situations, and weak governance, to name a few. SSF vulnerability has become more evident, with increased severity, during the COVID-19 pandemic. Knowledge about what makes SSF vulnerable is limited, which impedes appropriate policy responses and intervention. As a first step to rectifying the situation, a classification approach is proposed to better describe and differentiate types of vulnerability to SSF and to guide data collection and dissemination about SSF vulnerability. The classification system is developed based on a narrative review of case studies worldwide, published in scientific journals in the past 20 years. The case studies cover SSF in diverse aquatic environments, including river, floodplain, reservoir, river delta, lake, atoll, estuaries, lagoon mangrove, coral reefs, seagrass ecosystem, islands, coastal and marine environment. Similar to the five pillars of sustainability, SSF vulnerability is associated with five main factors, i.e., biophysical, social, economic, technological, and governance. Knowledge about SSF vulnerability helps inform tailored management strategies and policies to reduce SSF marginalization and promote viability, aligning, therefore, with the goal of the Voluntary Guidelines for Securing Sustainable Small-Scale Fisheries.Copyright © 2022 Elsevier Ltd

The skin damage in the control of COVID-2019 infections and strategy to guide the treatment in a new stage

Since the outbreak of the novel coronavirus in 2019, with the relentless efforts of the country in the early stage to the "10 new measures" now, the prevention and control has been gradually released from strict regulations. The number of COVID-19 infections increased, and wide attention has been attracted by the primary skin diseases, deterioration of pre-existing skin diseases, and other skin damage that resulted from self-protection and treatment. Considering the series of skin problems caused by COVID-19 infection and prevention measures, we mainly summarize the common skin damage after the"10 new measures" and propose a strategy to guide the treatment in this article.

Consensus Guidelines for Teledermatology: Scoping Review

Background: Consensus guidelines and recommendations play an important role in fostering quality, safety, and best practices, as they represent an expert interpretation of the biomedical literature and its application to practice. However, it is unclear whether the recent collective experience of implementing telemedicine and the concurrent growth in the evidence base for teledermatology have resulted in more robust guidance. Objective: The objective of this review was to describe the extent and nature of currently available guidance, defined as consensus guidelines and recommendations available for telemedicine in dermatology, with guidance defined as consensus or evidence-based guidelines, protocols, or recommendations. Methods: We conducted a single-reviewer scoping review of the literature to assess the extent and nature of available guidance, consensus guidelines, or recommendations related to teledermatology. We limited the review to published material in English since 2013, reflecting approximately the past 10 years. We conducted the review in November and December of the year 2022. Results: We identified 839 potentially eligible publications, with 9 additional records identified through organizational websites. A total of 15 publications met the inclusion and exclusion criteria. The guidelines focused on varied topics and populations about dermatology and skin diseases. However, the most frequent focus was general dermatology (8/15, 53%). Approximately half of the telemedicine guidance described in the publications was specific to dermatology practice in the context of the COVID-19 pandemic. The publications were largely published in or after the year 2020 (13/15, 87%). Geographical origin spanned several different nations, including Australia, the United States, European countries, and India. Conclusions: We found an increase in COVID-19-specific teledermatology guidance during 2020, in addition to general teledermatology guidance during the period of the study. Primary sources of general teledermatology guidance reported in the biomedical literature are the University of Queensland's Centre for Online Health and Australasian College of Dermatologists E-Health Committee, and the American Telemedicine Association. There is strong evidence of international engagement and interest. Despite the recent increase in research reports related to telemedicine, there is a relative lack of new guidance based on COVID-19 lessons and innovations. There is a need to review recent evidence and update existing recommendations. Additionally, there is a need for guidance that addresses emerging technologies. © Mollie R Cummins, Triton Ong, Julia Ivanova, Janelle F Barrera, Hattie Wilczewski, Hiral Soni, Brandon M Welch, Brian E Bunnell.

Cognition-oriented Facilitation and Guidelines for Collaborative Problem-solving Online and Face-to-face: An in-depth examination of format and facilitation influence on problem-solving performance

During the Covid-19 pandemic, more guidelines were created to teach people how to facilitate meetings online, but few were designed from a cognition-oriented perspective. Additionally, solving complex problems is essential in many occupations. However, the influence of online and face-to-face discussion formats on the performance in complex problem-solving tasks is unclear, even though remote working has become common over the past several few years. Hence, this study aims to answer two research questions: (a) Does problem-solving performance differ between online and face-to-face meetings? and (b) Does facilitation improve problem-solving performance when different formats are used? We conducted experiments with 40 groups using a 2 × 2 factorial design, which were controlled for both facilitation and format. Each group comprised two randomly selected participants, and each problem-solving discussion lasted between 1.5-2 h. The obtained evidence showed that format can influence the performance of balancing intercorrelated factors in a complex scenario, but it does not affect the performance of achieving a predefined goal. Instead, it we found that facilitation is helpful for achieving a predefined goal. Based on the results obtained, we propose future design directions for problem-solving centric computer-supported cooperative work systems from a cognition-oriented perspective. © 2023 Owner/Author.

The lived experiences of principals in the northeast United States in supporting the social-emotional wellbeing of their school community during the COVID-19 pandemic

This study investigated the lived experiences of (12) elementary and middle school principals in the Northeast United States throughout the COVID-19 pandemic. In light of the emergency COVID-19 guidelines that have been implemented across schools in the United States, the purpose of this phenomenological study was to understand how principals support the social-emotional wellbeing of their school community and make emergency policy decisions during crisis. Through virtual interviews, elementary and middle school principals shared their unique perspectives around the perceived impact that COVID-19 emergency guidelines had on their schools, actions they took to support their schools' socio-emotionally, and the ways in which they made decisions around emergency policy. The study revealed that leaders and teachers experienced higher levels of stress due to the COVID-19 emergency guidelines, and students had fewer opportunities for social interactions. Principals also had to leverage existing socio-emotional supports and develop innovative methods to promote the socio-emotional wellbeing of their school communities throughout the pandemic. Throughout the crisis, policy decisions were made by leaning on experts, considering safety and operational feasibility, and deliberating community perception. The ways in which principals individually perceived and interpreted emergency guidelines also influenced the decision-making process and implementation. School communities were impacted by emergency guidelines in profound ways and principals recognized the critical importance of supporting their school community socio-emotionally during crisis. Principals prioritized the overall safety of their school communities regardless of the impact on socio-emotional health. Lastly, this study provided recommendations not only for future policy in education, but potential practices that will provide targeted socio-emotional interventions to students and strengthen community connections. Recommendations for future studies are also included to help bring to light the degree COVID-19 emergency guidelines have impacted schools throughout the United States for generations to come. (PsycInfo Database Record (c) 2023 APA, all rights reserved)

COVID-19-specific adult basic life support guideline strategies for chiropractors and other healthcare providers to maximize the safety and efficacy of resuscitation: a commentary.

BACKGROUND: The emergence of an unprecedented novel severe acute respiratory syndrome coronavirus-2 (SARS-C0V-2), which causes the coronavirus disease 2019 (COVID-19) pandemic, has created new scenarios in basic life support (BLS) management. According to current evidence, SARS-CoV-2 can be transmitted airborne in aerosol particles during resuscitation. Research evidence found an alarming global increase in out-of-hospital cardiac arrests during the COVID-19 pandemic. Healthcare providers are legally obliged to respond to cardiac arrest as soon as possible. Chiropractors will likely encounter potential exercise-related and non-exercise-related cardiac emergencies at some point in their professional lives. They have a duty of care to respond to emergencies such as cardiac arrest. Chiropractors are increasingly involved in providing care, including emergency care, for athletes and spectators at sporting events. Also, exercise-related cardiac arrest in adult patients may occur during exercise testing or rehabilitation with exercise prescriptions in chiropractic and other healthcare settings. Little is known about the COVID-19 BLS guidelines for chiropractors. Knowledge of the current COVID-19-specific adult BLS guidelines is essential to developing an emergency response plan for the on-field and sideline management of exercise-related cardiac arrest and non-athletic, non-exercise-related cardiac arrest. MAIN TEXT: Seven peer-reviewed articles on the COVID-19-specific BLS guidelines, including two updates, were reviewed for this commentary. Responding to the COVID-19 pandemic, the national and international resuscitation organizations recommended interim COVID-19-specific BLS guidelines with precaution, resuscitation, and education strategies. BLS safety is paramount. A precautionary approach with the bare minimum of appropriate personal protective equipment for resuscitation is recommended. There was disagreement among the COVID-19 BLS guidelines on the level of personal protective equipment. All healthcare professionals should also undergo self-directed BLS e-learning and virtual skill e-training. The summarized COVID-19-specific adult BLS guideline strategies and protocols are tabled, respectively. CONCLUSIONS: This commentary provides a practical overview and highlights current evidence-based intervention strategies of the COVID-19-specific adult BLS guidelines that may help chiropractors and other healthcare providers reduce BLS-related exposures to SARS-CoV-2 and the risks of SARS-CoV-2 transmission and maximize the efficacy of resuscitation. This study is relevant to and impacts future COVID-19-related research in areas such as infection prevention and control.

Paper and screen media in current health education practices aimed at older adults: a scoping review protocol.

INTRODUCTION: With technological advancement and the COVID-19 pandemic, paper-based media are giving way to screen-based media to promote healthy ageing. However, there is no review available covering paper and screen media use by older people, so the objective of this review is to map the current use of paper-based and/or screen-based media for health education aimed at older people. METHODS AND ANALYSIS: The literature will be searched in Scopus, Web of Science, Medline, Embase, Cinahl, The ACM Guide to Computing Literature and Psyinfo databases. Studies in English, Portuguese, Italian or Spanish published from 2012 to the date of the search will be examined. In addition, an additional strategy will be carried out, which will be a Google Scholar search, in which the first 300 studies according to Google's relevance algorithm will be verified. The terms used in the search strategy will be focused on older adults, health education, paper-based and screen-based media, preferences, intervention and other related terms. This review will include studies where the average age of the participants was 60 years or older and were users of health education strategies through paper-based or screen-based media. Two reviewers will carry out the selection of studies in five steps: identification of studies and removal of duplicates, pilot test, selection by reading titles and abstracts, full-text inclusion and search for additional sources. A third reviewer will resolve disagreements. To record information from the included studies, a data extraction form will be used. The quantitative data will be presented in a descriptive way and the qualitative data through Bardin's content analysis. ETHICS AND DISSEMINATION: Ethical approval is not applicable to the scoping review. The results will be disseminated through presentations at significant scientific events and published in journals in the area. PROTOCOL REGISTRATION NUMBER: Open science framework (DOI: DOI 10.17605/OSF.IO/GKEAH).

Management of Hand Surgery Services during the Novel Coronavirus Disease 2019 Pandemic.

Introduction The novel coronavirus disease 2019 (COVID-19) pandemic is an international public health emergency. Health systems must plan for the increasing requirements for critical care during the COVID-19 pandemic. The aim of this article is to offer strategies for hand surgeons to planning and implementing their response during the COVID-19 pandemic and in the subsequent phases to preserve health care system functioning. Materials and Methods Assessment of the principles of management related to COVID-19 management to develop pandemic preparedness and response protocols pertinent to patients, health care workers, and health systems. Results Strategies for the reorganizing hand surgery practice and a set of recommendations that should facilitate the process of rescheduling both out-patient service and surgical activities during the COVID-19 and its subsequent phases are suggested. Conclusion During the COVID-19 pandemic, management of patients requiring specialist care for hand conditions should be adapted to limit the risks associated with the virus without jeopardizing outcomes. These expedient recommendations during extraordinary circumstances are a foundation for further discussion on the topic as the COVID-19 pandemic evolves.

Have News Reports on Suicide and Attempted Suicide During the COVID-19 Pandemic Adhered to Guidance on Safer Reporting?

Background: Associations between sensational news coverage of suicide and increases in suicidal behavior have been well documented. Amid growing concern over the impact of the COVID-19 pandemic on suicide rates, it is especially important that news coverage adheres to recommended standards. Method: We analyzed the quality and content of print and online UK news reports of possible COVID-19-related suicides and suicide attempts in the first 4 months of the pandemic (N = 285). Results: The majority of reports made explicit links between suicidal behavior and the COVID-19 pandemic in the headline (65.5%), largely based on statements by family, friends, or acquaintances of the deceased (60%). The impact of the pandemic on suicidal behavior was most often attributed to feelings of isolation (27.4%), poor mental health (14.7%), and entrapment due to government-imposed restrictions (14.4%). Although rarely of poor overall quality, reporting was biased toward young people, frontline staff, and relatively unusual suicides and, to varying degrees, failed to meet recommended standards (e.g., 41.1% did not signpost readers to sources of support). Limitations: This analysis cannot account for the impact of reporting on suicide. Conclusion: Careful attention must be paid to the quality and content of reports, especially as longer-term consequences of the pandemic develop.

JBI systematic review protocol of text/opinions on how to best collect race-based data in healthcare contexts.

INTRODUCTION: Racialized population groups have worse health outcomes across the world compared with non-racialized populations. Evidence suggests that collecting race-based data should be done to mitigate racism as a barrier to health equity, and to amplify community voices, promote transparency, accountability, and shared governance of data. However, limited evidence exists on the best ways to collect race-based data in healthcare contexts. This systematic review aims to synthesize opinions and texts on the best practices for collecting race-based data in healthcare contexts. METHODS AND ANALYSES: We will use the Joanna Briggs Institute (JBI) method for synthesizing text and opinions. JBI is a global leader in evidence-based healthcare and provides guidelines for systematic reviews. The search strategy will locate both published and unpublished papers in English in CINAHL, Medline, PsycINFO, Scopus and Web of Science from 1 January 2013 to 1 January 2023, as well as unpublished studies and grey literature of relevant government and research websites using Google and ProQuest Dissertations and Theses. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement methodology for systematic reviews of text and opinion will be applied, including screening and appraisal of the evidence by two independent reviewers and data extraction using JBI's Narrative, Opinion, Text, Assessment, Review Instrument. This JBI systematic review of opinion and text will address gaps in knowledge about the best ways to collect race-based data in healthcare. Improvements in race-based data collection, may be related to structural policies that address racism in healthcare. Community participation may also be used to increase knowledge about collecting race-based data. ETHICS AND DISSEMINATION: The systematic review does not involve human subjects. Findings will be disseminated through a peer-reviewed publication in JBI evidence synthesis, conferences and media. PROSPERO REGISTRATION NUMBER: CRD42022368270.

Mortality burden due to ambient nitrogen dioxide pollution in China: Application of high-resolution models.

BACKGROUND: A large gap exists between the latest Global Air Quality Guidelines (AQG 2021) and Chinese air quality standards for NO2. Assessing whether and to what extent air quality standards for NO2 should be tightened in China requires a comprehensive understanding of the spatiotemporal characteristics of population exposure to ambient NO2 and related health risks, which have not been studied to date. OBJECTIVE: We predicted ground NO2 concentrations with high resolution in mainland China, explored exposure characteristics to NO2 pollution, and assessed the mortality burden attributable to NO2 exposure. METHODS: Daily NO2 concentrations in 2019 were predicted at 1-km spatial resolution in mainland China using random forest models incorporating multiple predictors. From these high-resolution predictions, we explored the spatiotemporal distribution of NO2, population and area percentages with NO2 exposure exceeding criterion levels, and premature deaths attributable to long- and short-term NO2 exposure in China. RESULTS: The cross-validation R2and root mean squared error of the NO2 predicting model were 0.80 and 7.78 µg/m3, respectively,at the daily level in 2019.The percentage of people (population number) with annual NO2 exposure over 40 µg/m3 in mainland China in 2019 was 10.40 % (145,605,200), and it reached 99.68 % (1,395,569,840) with the AQG guideline value of 10 µg/m3. NO2 levels and population exposure risk were elevated in urban areas than in rural. Long- and short-term exposures to NO2 were associated with 285,036 and 121,263 non-accidental deaths, respectively, in China in 2019. Tightening standards in steps gradually would increase the potential health benefit. CONCLUSION: In China, NO2 pollution is associated with significant mortality burden. Spatial disparities exist in NO2 pollution and exposure risks. China's current air quality standards may no longer objectively reflect the severity of NO2 pollution and exposure risk. Tightening the national standards for NO2 is needed and will lead to significant health benefits.